Items are found throughout the game. They appear after taking down an enemy or destroying parts of the environment. Items are also random, so don't expect to find the same one twice in a certain area. While basic equipment is common in the early stages of the game, rare and special items have to be won in special danger room sessions or purchased from Forge or the Healer. Be sure to sell back extra items and swap out old ones as the game progresses.
| Backpacks | ||
| Item | Effect | Buy /Sell Value |
| Basic Power Enhancer | + 9-11 damage on mutant attack. | 2000/500 |
| Basic Targeting Implant | + 2% criticals for ranged attack. | 1500/375 |
| Basic Weakness Analyzer | +2% critical for melee attack. | 2000/5001 |
| Basic Tissue Generator | Regenerate 2 health per second. Up to 25% after 5 sec. idle | 1000/2501 |
| Basic DNA Generator | Generate mutant energy 25% faster | 2000/500 |
| Basic Muscle Accelerator | Attack, run speed +10% | 2000/5001 |
| Power Enhancer | + 23-31 damage on mutant attack. | 3000/7501 |
| Targeting Implant | + 4% criticals for ranged attack. | 3000/750 |
| Weakness Analyzer | +4% critical for melee attack. | 4000/1000 |
| Tissue Generator | Regenerate 4 health per second. Up to 50% after 5 sec. idle | 3000/750 |
| DNA Generator | Generate mutant energy 50% faster | 3000/750 |
| Muscle Accelerator | Attack, run speed +20% | 3000/750 |
| Super Power Enhancer | +80-100 damage on mutant attack. | 4000/1000 |
| Super Targeting Implant | + 6% criticals for ranged attack. | 4500/1125 |
| Super Weakness Analyzer | +6% critical for melee attack. | 6000/1500 |
| Super Tissue Generator | Regenerate 6 health per second. Up to 75% after 5 sec. idle | 6000/1500 |
| Super DNA Generator | Generate mutant energy 75% faster | 4000/1000 |
| Super Muscle Accelerator | Attack, run speed +30% | 4000/1000 |
| Ultra Power Enhancer | + 23-31 damage on mutant attack. | 5000/1250 |
| Ultra Targeting Implant | + 8% criticals for ranged attack. | 6000/1500 |
| Ultra Weakness Analyzer | +8% critical for melee attack. | 8000/2000 |
| Ultra Tissue Generator | Regenerate 8 health per second. Up to 100% after 5 sec. idle | 10,000/2500 |
| Ultra DNA Generator | Generate mutant energy 100% faster | 2000/1250 |
| Ultra Muscle Accelerator | Attack, run speed +40% | 5000/1250 |
| Unique Backpacks | ||
| Item | Effect | Buy /Sell Value |
| Astral Stone | +3 focus, +9-11 damage on shadow fiends. | NA |
| Belt of Unus | -13 damage, 20% chance for deflecting beam damage, level 32 required | NA/4125 |
| Bands of the Beast | +20% damage for Beast's mutant powers, +5 strike. | NA |
| Cannonball's Flame | -8 damage, +100-125 for flying melee attacks. level 15 required. | 4500/1485 |
| Flight of the Northstar | 30% longer flight, +20% knockback attack. Level 10 required. | 2500/825 |
| The X-Cutioner Hood | Generate energy 50% faster, +80-100 damage on mutants. | NA/2145 |
| Sunfire's Mask | -20% fire damage, +9-11 fire damage for mutant attacks. | 4500/1485 |
| Shadowcat's Touch | -5 damage, +25-31 punch and kick vs. robots. Level 15 required. | 4500/1485 |
| Winter's Fury | +20% for Iceman's attacks, +5 body | NA |
| Visor of Retribution | +20 optic damage for Cyclops, +5 focus | 4500/1485 |
| Shi'Ar Battle Implants | +3 to everything | NA |
| Shi'Ar Body Shield | +50% physical resistance | NA |
| Shi'Ar Energy Armor | +50% energy resistance | NA |
| Shi'Ar mind gem | +50% mental resistance | NA |
| Mask of Xorn | Mutant Energy is always full. | NA |
| Belts | ||
| Item | Effect | Buy /Sell Value |
|
Basic Strike Enhancer |
Striking +1 | 1000/250 |
| Basic Agility Enhancer | Agility +1 | 1000/250 |
| Basic Body Enhancer | Body +1 | 1000/250 |
| Basic Focus Enhancer | Focus +1 | 1000/2501 |
| Strike Enhancer | Striking +2 | 3000/7501 |
| Agility Enhancer | Agility +2 | 3000/750 |
| Body Enhancer | Body +2 | 4000/1000 |
| Focus Enhancer | Focus +2 | 2000/500 |
| Super Strike Enhancer | Striking +4 | 4000/1000 |
| Super Agility Enhancer | Agility +4 | 4500/1125 |
| Super Body Enhancer | Body +4 | 4000/1000 |
| Super Focus Enhancer | Focus +4 | 4000/1000 |
| Ultra Strike Enhancer | Striking +8 | 8000/200 |
| Ultra Agility Enhancer | Agility +8 | 8000/2,000 |
| Ultra Body Enhancer | Body +8 | 8000/2000 |
| Ultra Focus Enhancer | Focus +8 | 8,000/2,000 |
| Armor | ||
| Item | Effect | Buy /Sell Value |
| Basic Nanofiber Armor | -5 damage | 1000/250 |
| Basic Harmonic Deflector | +10 Chance to reflect 15-18 Beam damage | 1000/250 |
| Basic Psionic Deflector | +10 Chance to reflect 15-18 Psionic damage | 1000/250 |
| Basic Electron Deflector | +10 Chance to reflect 15-18 Electron damage | 1000/2501 |
| Basic Elemental Deflector | +10 Chance to reflect 15-18 Elemental damage | 3000/7501 |
| Basic Inertial Dampener | -20% Knockback | 3000/750 |
| Basic Inertial Deflector | +10% chance to reflect 15-18 punch/kick damage | 4000/1000 |
| Nanofiber Armor | Focus +2 | 2000/500 |
| Harmonic Deflector | Striking +4 | 4000/1000 |
| Psionic Deflector | Agility +4 | 4500/1125 |
| Electron Deflector | Body +4 | 4000/1000 |
| Elemental Deflector | Focus +4 | 4000/1000 |
| Inertial Dampener | Striking +8 | 8000/200 |
| Inertial Deflector | Agility +8 | 8000/2,000 |
| Ultra Body Enhancer | Body +8 | 8000/2000 |
| Ultra Focus Enhancer | Focus +8 | 8,000/2,000 |